FAMILIAL CANCER CLINIC

ABOUT US

AIIMS HBOC REGISTRY

Breast and Ovarian cancers rank the 1st and 3rd commonest cancers among women in India accounting for 2,00,000 new cases a year. 10-15% of these cancers are hereditary, i.e., occur in different generations of the same family due to mutations in genes like BRCA1, BRCA2, TP53, CHEK2, PALB2, RAD50, etc. Identification of these families by appropriate genetic testing gives a remarkable opportunity to save lives by “precision prevention”. Through proper surveillance and risk-reducing surgeries, we can prevent new cancers in these patients and their unaffected children, siblings, and other family members.

Recognizing these high-risk families is a huge unmet need in India where cancer genetic clinics are rare. Detecting mutations in one patient gives leads to the detection of unsuspected mutations in their unaffected family members, by cascade single-site testing. Thus, accurate testing is the key to the success of such precision prevention programs.

Specialization

Hereditary Cancer Analysis
Pre-Test Genetic Counselling
Post Test Genetic Counselling
Preservation of germline DNA for future research.
Public awareness related to hereditary breast and ovarian cancers.
Analyze and mitigate the anxiety and stress levels among patients and family members in HBOC families.

Mission

To promote the identification of families with hereditary cancer
To encourage the participation in surveillance programs of individuals at high risk.
To ensure the continuity of lifelong surveillance examinations.
To promote research, particularly in the improvement of surveillance protocols.

Goals

To establish a registry of patients and families diagnosed with hereditary breast and/or ovarian cancers at AIIMS, New Delhi, and NCI-AIIMS, Jhajjar.
To establish a repository of germline DNA of these patients.
To establish an online database of germline mutations associated with HBOC in India.
Record de-identified data of high-risk patients in a HIPAA-compliant system: Clinical details, pedigree, treatment, and survival outcomes.
To give timely updates for screening to the patients and unaffected relatives with mutations (carriers).
To organize public awareness programs to communicate the importance of recognizing HBOC in the population.

Meet Our Experienced & Dedicated Team

Dr. Raja Pramanik, Principal Investigator Associate Professor, Medical Oncology

Prof. SVS Deo, Co-Investigator Professor and Head of Department, Surgical Oncology

Dr. Neerja Bhatla Professor & Head , Department of Obstetrics & Gynaecology

Dr. Ritu Gupta Professor, Laboratory Oncology

Dr. Sanjay Thulkar Professor, Radio Diagnosis

Dr. Ajay Gogia Additional Professor, Medical Oncology

Dr. Sachin Khurana Associate Professor, Medical Oncology

Dr. Atul Batra Associate Professor, Medical Oncology

Dr. Akash Kumar Assistant Professor, Medical Oncology

Dr. Ashutosh Mishra Assistant Professor

Dr. Babul Bansal Assistant Professor, Department of Surgical Oncology

Dr. Seema Singhal Additional Professor, Department of Obstetrics and Gynaecology

Dr. Ekta Dhamija Additional Professor, Radio-Diagnosis

Dr. Aparna Sharma Assistant Professor, Department of Medical Oncology National Cancer Institute, AIIMS Jhajjar

Dr. Punit Kaur Professor & Head of the Department, Biophysics

Dr. Deepshi Thakral, Co-Investigator Scientist II, Laboratory Oncology

Dr. Koushik Sinha Deb Assistant Professor, Department of Psychiatry

Dr. D.N Sharma, Patron Professor and Head of Radiation Oncology, Department of Radiation Oncology

Dr. Atul Sharma, Patron Professor And Head, Department Of Medical Oncology

Dr. Sameer Bakhshi, Patron Professor, Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi

Dr. Sandeep R. Mathur, Patron Professor, Department of Pathology

Dr. (Major) Mukurdipi Ray, Patron Professor, Surgical Oncology

Olufunmilayo I. Olopade, Advisors MD Walter L. Palmer Distinguished Service Professor Of Medicine Professor Of Human Genetics Director, Center For Clinical Cancer Genetics And Global Health